Popular Decongestant Medicine Found Ineffective: FDA Document

Contact Your Elected Officials
The Epoch Times Header

Colds, flu, or allergies can send you running to the medicine aisle looking for nasal decongestants that claim to relieve symptoms and unblock a stuffy nose.

But the active ingredient in many of them, called phenylephrine (PE), doesn’t offer any real benefits when taken orally, according to the U.S. Food and Drug Administration (FDA). In fact, it may even cause harm, according to Dr. William Schaffner, an infectious disease specialist and professor at Vanderbilt University School of Medicine.

“I would hope that [the drugs] would be withdrawn because there’s no point in taking ineffective medication,” he told The Epoch Times, noting that phenylephrine is a medication that can increase heart rate and cause problems for some people.

Why Use Phenylephrine?

It began with the fight against methamphetamine trafficking. Since pseudoephedrine can be used in the illicit manufacture of this drug, the FDA responded with the Combat Methamphetamine Epidemic Act, which became law in 2006. It banned the OTC sale of medicines containing pseudoephedrine, ephedrine, and phenylpropanolamine. Customers now must request these medications from pharmacy staff.

This left OTC drugs containing phenylephrine as the only easily accessible option.

While the drug’s safety remains unquestioned, the FDA investigated phenylephrine’s efficacy and determined it simply doesn’t work.

This week, the FDA released a briefing (pdf) of its investigation as background for an advisory committee meeting that will decide whether to revoke oral phenylephrine’s “generally recognized as safe and effective” (GRASE) designation due to lack of efficacy.

The briefing noted there is a reasonable expectation that, when used as directed, the drug should provide clinically significant symptom relief. However, reviewers found oral phenylephrine is not an effective nasal decongestant at either the recommended 10-milligram dose every four hours or at higher 40-milligram doses. An effective oral dose of PE for nasal decongestion is unknown.

Phenylephrine is not the only ineffective OTC medication. Others include:

  • Guaifenesin as a cough medicine used to clear mucus from the airways.
  • Dextromethorphan as a cough suppressant for upper respiratory infections.

By George Citroner

Read Full Article on TheEpochTimes.com

The Epoch Times
The Epoch Timeshttps://www.theepochtimes.com/
Tired of biased news? The Epoch Times is truthful, factual news that other media outlets don't report. No spin. No agenda. Just honest journalism like it used to be.

All Apologies For the Culture War Slop

"Forgive me for ignoring the elite-driven political/economic excesses, focusing instead on divisive culture war slop."

Rising sea levels are less of a threat than we were told

New study challenges climate alarmism: sea levels aren't rising faster than the past century, despite dire warnings of floods and mass migrations.

President Trump is Being Wrongfully Obstructed on Tariffs

Podcaster Zach De Gregorio, in “Wolves And Finance,” delivers a sharp editorial unpacking the truth behind Trump’s international tariff policies.

Trump And Kennedy Are Placing Patients First

Trump admin set rules requiring hospitals and insurers to give patients clear price info, aiming to boost transparency and put patients first.

Figures flip the field

Sports programs with strong donor bases and NIL collectives are flipping recruits and transfers at rapid speed, like traders on Wall Street.

Appeals Court Upholds $83 Million Ruling Against Trump

A federal appeals court upheld a jury ruling ordering Trump to pay columnist E. Jean Carroll $83.3M in damages for defaming her.

Video Shows Fatal Stabbing of Ukraine War Refugee: What to Know

Video shows moments before Ukrainian refugee Iryna Zarutska was killed on a Charlotte light rail, raising new concerns over crime and public safety.

Border Czar Says ICE Will Target More Businesses After Enforcement Operation at Hyundai

Trump administration to expand immigration enforcement, targeting more businesses after detaining hundreds at a Georgia Hyundai plant.

Education Department to Issue Guidance Protecting Right to Prayer, Trump Says

President Donald Trump on Sept. 8 announced that the Department of Education will issue new guidance protecting the right to prayer.

Trump Runs out of Patience With China, Sharpens His Words

President Donald Trump’s recent remarks targeting China and its allies mark a noticeable shift in tone.

Trump Signs Order Renaming Department of Defense as Department of War

President Donald Trump on Sept. 5 signed an executive order renaming the Department of Defense as the Department of War.

Trump Signs Executive Order Targeting Countries That Unlawfully Detain Americans

President Trump signed an EO on targeting the unlawful detention of American citizens around the world and to facilitate the release of hostages.

Trump Sends Warning to Venezuela After US Military Strikes Boat Allegedly Carrying Drugs

President Trump sent a warning to Venezuela after the U.S. military struck what the administration says was a boat carrying drugs in the Caribbean.
spot_img

Related Articles

Popular Categories

MAGA Business Central