Vaccine Antibodies Decline 7 Months After Second Shot: US Study

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Antibody levels generated by two shots of the Pfizer-BioNTech vaccine can undergo up to a 10-fold decrease seven months following the second vaccination, research suggests.

The drop in antibody levels will compromise the bodyโ€™s ability to defend itself against COVID-19 if the individual becomes infected.

In a recent BioRxiv study published ahead of peer-review, many recipients of the vaccine displayed substantial waning of antibodies to the CCP (Chinese Communist Party) virus, or SARS-CoV-2, and its variants including Delta, Beta, and Mu.

Bali Pulendran of Stanford University and Mehul Suthar of Emory University told Reuters that the study shows โ€œvaccination with the Pfizer-BioNtech vaccine induces high levels of neutralizing antibodies against the original vaccine strain, but these levels drop by nearly 10-fold by seven months.โ€

While the body has other defense mechanisms in place to ward off the virus, Pulendran and Suthar added that antibodies โ€œare critically important in protecting against SARS-CoV-2 infection.โ€

The study focused on 46 healthy participants who had received two doses of the Pfizer-BioNTech vaccine. The participantsโ€™ blood was tested once after receiving the second vaccination and once again after six months.

Researchers suggested administering a third booster vaccination as a measure to improve vaccine efficacy.

Earlier reports of data from a phase one study showed that participants had a higher level of neutralization antibody titers against the CCP virusโ€™s Delta variant after getting a boosterโ€”a third doseโ€”versus those who just received two doses, officials said.

โ€œThe third dose elevates the neutralizing antibodies in our laboratory studies to up to 100 times higher levels [after the third dose] compared to [before],โ€ Mikael Dolsten, Pfizerโ€™s chief scientific officer, told investors in a call earlier this year.

The two-dose Pfizer vaccine was found to beย 96 percent effective for the first two months following the second dose, according to a July 28ย study from the companiesโ€™ scientists.

Byย Tammy Hung

Read Full Article on TheEpochTimes.com

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