The clearinghouse website will also offer comparison shopping and click-through options to home-delivery pharmacies.
Consumers can now find more than 600 discounted generic medications through TrumpRx.gov and have them delivered to their homes, President Donald Trump announced from the White House on May 18.
The site will also include new functionality, allowing consumers to compare brand-name and generic prices, as well as get home delivery on medications through partnerships with mail-order pharmacies.
With these additions, TrumpRx will feature the best and lowest prices on prescriptions used by tens of millions of Americans, Trump said.
Generic drugs are often much less expensive than their brand-name counterparts.
“In some cases the discounted generics … may be offered at an even lower cash price than the out-of-pocket insurance cost,” the president said.
Trump announced the site in September 2025 when unveiling a most-favored-nation price agreement with Pfizer.
Since then, 17 pharmaceutical companies have entered most-favored-nation agreements with the administration and have agreed to offer medications through TrumpRx.
The site has drawn 10 million users over the past three months, saving consumers more than $400 million, Trump said.
The Council of Economic Advisers estimates that these most-favorite-nation drug policies will save Americans nearly $600 billion over 10 years.
Before the addition of generic medications, 874 drugs were listed on TrumpRx.gov. The administration started TrumpRx on Feb. 5 to facilitate direct-to-consumer prescription drug sales in keeping with the president’s most-favored-nation drug pricing policy.
Executives from discount drug retailers, including Mark Cuban, founder of Mark Cuban Cost Plus Drug Company; Tanvi Patel, vice president of Amazon Pharmacy; and Aaron Crittenden, president of RX Marketplace at Good Rx, joined Trump for the announcement.
Expanded functionality on the site allows consumers to compare the cost of brand-name and generic drugs, find nearby pharmacies offering the medication, or click through to discount retailers to purchase drugs for home delivery.
“TrumpRx has created transparency with no middlemen,” Dr. Mehmet Oz, administrator of the Centers for Medicare and Medicaid services, said.
